A nucleoside analog with antiviral properties; inhibits replication of laboratory and clinical isolate wild-type and polV74 mutant HIV viruses in PBMCs (IC50s = 0.3-1.4 and 1.1-11.2 μM for wild-type and pol74 mutant strains, respectively); decreases the number of HIV-infected mice (IC50 = 13.7 mg/kg per day, i.p. starting the day before infection with HIV) in a SCID-hu mouse model of human hematolymphoid engrafted organs