Immunocytochemistry: 2-3 μg/mL, Immunofluorescence: 2-3 μg/mL, Western Blot: 2-3 μg/mL
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Description
HK2 Antibody (2H8L6), ABfinity? Rabbit Monoclonal. In vertebrates there are four major glucose-phosphorylating isoenzymes, designated hexokinase I, II, III, and IV. Hexokinase activity is involved in the first step in several metabolic pathways including phosphorylation of glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Hexokinase is an allosteric enzyme inhibited by its product GLC-6-P. Hexokinase 2 is the predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle. Expression of this gene is insulin-responsive, and studies in rat suggest that it is involved in the increased rate of glycolysis seen in rapidly growing cancer cells.
Immunogen
n/a
Other Names
HK II, hexokinase type II, hexokinase-2, hexokinase-2 muscle, muscle form hexokinase