A peptide hormone; binds to CCK receptors on human gastric leiomyosarcoma cells (IC50 = 0.9 nM) and in guinea pig gallbladder and pancreatic tissue (IC50s = 1.7 and 2.5 μM, respectively); increases levels of cytosolic calcium in isolated rabbit stomach parietal cells (EC50 = 11 nM) and stimulates pepsinogen secretion by isolated human peptic cells (ED50 = 30 nM); increases gastric acid secretion in vivo in rats (1 nmol/kg/h)
Size
1 mg
Concentration
n/a
Applications
n/a
Other Names
Gastrin Heptadecapeptide I (human)|Gastrin I (1-17) (human)