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| Antigenic Specificity | Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 40 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Glutamic Acid Decarboxylase (GAD) catalyzes the conversion of glutamate to gamma-aminobutyric acid (GABA), the principal inhibitory neurotransmitter in the brain. There are two isoforms of GAD, GAD65 (GAD2) and GAD67 (GAD1) (65 and 67 kDa, respectively) encoded by two different genes. With 64% amino acid identity, the two isoforms have distinct intraneuronal distribution in the brain. The highest degree of diversity appears to be located at the N-terminus. Primarily found in nerve terminals, GAD65 is required for targeting the enzyme to GABA-containing secretory vesicles. GAD67 is thought to be primarily located in the nerve cell body and has been identified as a major autoantigen in type 1 diabetes.Rabbit Anti-GAD65 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from N-terminal of human GAD65 (Swiss Prot: Q05329). |
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| Immunogen | KLH-coupled synthetic peptide from N-terminal of human GAD65 . |
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| Other Names | GAD65|gad65|F12P19.12|F12P19_12|GLUTAMATE DECARBOXYLASE 2|glutamate decarboxylase 2|zgc:112198|6330404F12Rik|GAD(65)|Gad-2 |
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| Gene, Accession # | Gene ID: 2572 |
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| Catalog # | ABIN1574149 |
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| Price | |
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| Order / More Info | Glutamate Decarboxylase 2 (Pancreatic Islets and Brain, 65kDa) (GAD2) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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