Solute Carrier Family 6 (Neurotransmitter Transporter, Glycine), Member 5 (SLC6A5) (aa 700-790)
Clone
polyclonal
Host Species
Rabbit
Reactive Species
human, rat, mouse
Isotype
n/a
Format
serum
Size
100 μL
Concentration
n/a
Applications
Immunohistochemistry (IHC),Western Blotting (WB)
Reviews / Ratings
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Description
FUNCTION: Terminates the action of glycine by its high affinity sodium-dependent reuptake into presynaptic terminals. May be responsible for the termination of neurotransmission at strychnine-sensitive glycinergic synapses. Defects in SLC6A5 are the cause of hyperekplexia type 3 (HKPX3) SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein Tissue specificity: Expressed in medulla, and to a lesser extent in spinal cord and cerebellum.Synonyms: Sodium- and chloride-dependent glycine transporter 2, GlyT-2, GlyT2, Solute carrier family 6 member 5, GLYT2, NET1
Immunogen
A synthetic peptide from aa region 700-790 of human SLC6A5 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.