A depsipeptide antifungal; inhibits ERG synthesis (IC50 = 12 ng/ml); inhibits ERG25p, a C-4 methyl oxidase (MIC = 12.5 μg/ml); selectively inhibits growth of C. albicans (MIC = 8 μg/ml); acts synergistically with fluconazole to reduce growth of azole-resistant C. albicans (MIC = 0.0078 μg/ml); a more polar form of PF-1163B
Size
500 μg
Concentration
n/a
Applications
n/a
Other Names
PF1163 A PF1163A fungus N-methyltyrosine anti-fungal 9-hydroxytetradecanoic aspergillus