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| Antigenic Specificity | Serrate RNA Effector Molecule Homolog (Arabidopsis) (SRRT) (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | antigen affinity purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ARS2(Arsenite-resistance protein 2) confers arsenite resistance The protein belongs to the ARS2 family. Arsenic is a human carcinogen whose mechanism of action is unknown. The arsenite acts as a comutagen by interfering with DNA repair. Two genes, ASR1(Arsenite-resistance protein 1) and ASR2(Arsenite-resistance protein 2), confer arsenite resistance to arsenite-sensitive cells. ASR1 shows almost complete homology with the rat fau gene, a tumor suppressor gene which contains a ubiquitinlike region fused to S30 ribosomal protein. Arsenite inhibits ubiquitin-dependent proteolysis. The tumor suppressor fau gene product or some other aspect of the ubiquitin system may be a target for arsenic toxicity and that disruption of the ubiquitin system may contribute to the genotoxicity and carcinogenicity of arsenite. |
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| Immunogen | Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human ARS2 (Arsenite-resistance protein 2) |
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| Other Names | CG7843|Dmel\\CG7843|anon-WO0118547.166|ars2|ars2-A|serrate|ARS2|ASR2|2810019G02Rik|ASR2A|ASR2B|ASR2C|ASR2D|Ars2|Asr2|MGC92060|CHUNP6881|zgc:92060 |
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| Gene, Accession # | Gene ID: 51593,83701 |
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| Catalog # | ABIN965596 |
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| Price | |
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| Order / More Info | Serrate RNA Effector Molecule Homolog (Arabidopsis) (SRRT) (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 11239002, 15345747, 10069470 |
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