Flow Cytometry: 1:100, Immunohistochemistry (Paraffin): 1:150, Western Blot: 1:1000
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Description
RAMP2 Monoclonal Antibody (OTI4E5). The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core gl
Immunogen
n/a
Other Names
CRLR activity-modifying protein 2, calcitonin receptor-like receptor activity modifying protein 2, calcitonin-receptor-like receptor activity-modifying protein 2, receptor (calcitonin) activity modifying protein 2, receptor activity modifying protein 2, receptor activity-modifying protein 2, receptor-activity-modifying protein 2