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Description
IL3 is a hematopoietic growth factor that promotes the survival, differentiation and proliferation of committed progenitor cells of the megakaryocyte, granulocyte-macrophage, erythroid, eosinophil, basophil and mast cell lineages. Produced by T cells, mast cells and eosinophils, IL3 enhances thrombopoieses, phagocytosis, and antibody-mediated cellular cytotoxicity. Its ability to activate monocytes suggests that IL3 may have additional immunoregulatory roles. Many of the IL3 activities depend upon co-stimulation with other cytokines. IL3 is species-specific, variably glycosylated cytokine. Synonyms: Monoclonal IL2Ra antibody, Anti-IL2Ra antibody, IL-3 antibody, Interleukin 3 antibody,MCGF antibody, Mast cell growth factor antibody, Multi-CSF antibody, HCGF antibody, P-cell stimulation factor antibody.
Immunogen
IL2 Ra antibody was raised in mouse using recombinant human soluble IL-2 Receptor alpha as the immunogen.