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| Antigenic Specificity | NUP98 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μL |
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| Concentration | n/a |
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| Applications | Immunoprecipitation: 2-5 μg/mg lysate, Western Blot: 1:2,000-1:10,000 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NUP98 Polyclonal Antibody. Signal-mediated nuclear import and export proceed through the nuclear pore complex (NPC), which is comprised of approximately 50 unique proteins collectively known as nucleoporins. The 98 kDa nucleoporin is generated through a biogenesis pathway that involves synthesis and proteolytic cleavage of a 186 kDa precursor protein. This cleavage results in the 98 kDa nucleoporin as well as a 96 kDa nucleoporin, both of which are localized to the nucleoplasmic side of the NPC. Rat studies show that the 98 kDa nucleoporin functions as one of several docking site nucleoporins of transport substrates. The human gene has been shown to fuse to several genes following chromosome translocations in acute myelogenous leukemia (AML |
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| Immunogen | n/a |
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| Other Names | GLFG-repeat containing nucleoporin; Nup98-Nup96; OTTHUMP00000013954; nuclear pore complex protein Nup98-Nup96 |
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| Gene, Accession # | Entrez: 4928; Uniprot: P52948 |
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| Catalog # | A301-786A |
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| Price | |
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| Order / More Info | NUP98 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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