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| Antigenic Specificity | Serotonin Receptor 1A (HTR1A) (aa 404-422), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 μg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | HTR1A(5-HYDROXYTRYPTAMINE RECEPTOR 1A), also called SEROTONIN 5-HT-1A RECEPTOR or BETA-2-ADRENERGIC RECEPTOR-LIKE PROTEIN G-21, is a subtype of 5-HT receptor that binds the endogenous neurotransmitter serotonin. It is a G protein-coupled receptor(GPCR) that is coupled to Gi/Go and mediates inhibitory neurotransmission. HTR1A denotes the human gene encoding for the receptor.The HTR1A gene is located at 5q12.3. The decreases in 5-HT-1A receptor densities correlated with decreased glucose utilization as measured by PET scan. Activation of 5-HT-1A receptors has been demonstrated to impair cognition, learning, and memory by inhibiting the release of glutamate and acetylcholine in various areas of the brain. 5-HT-1A receptors in the dorsal raphe nucleus are co-localized with neurokinin 1(NK1) receptors and have been shown to inhibit the release of substance P, their endogenous ligand. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT1A Receptor(404-422aa NKDFQNAFKKIIKCKFCRQ), different from the related rat and mouse sequences by one amino acid. |
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| Other Names | 5-HT-dro2A|5-HT1ADro|5-HT[1A]Dro|5-HT[[1ADro]]|5-HT[[1A]]|5-HT[[1A]]DRO|5HT-R2A|5HT-dro2A|5HT-drp[[2A]]|5HT1A|5HT[[1ADro]]|5htdro2a|CG16720|DRO2A|Dm5HTdro2A|Dmel\\CG16720|d5-HT1A|5htr1a|htr1a|HTR1A|Htr1a|5-Ht1a|Gpcr18|5-HT-1A|5-HT1A|5HT1a|ADRB2RL1|ADRBRL1|G-21|PFMCD|RAT5HT1A|5ht1a|adrb2rl1|adrbrl1|htr1a-A |
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| Gene, Accession # | Gene ID: 3350,24473 |
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| Catalog # | ABIN1673126 |
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| Price | |
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| Order / More Info | Serotonin Receptor 1A (HTR1A) (aa 404-422), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 2591972 |
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