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Description
Arginase 1 Monoclonal Antibody (sl6arg), eFluor 660, eBioscience?. Arginase-1 (ARG1) catalyzes the hydrolysis of L-arginine into ornithine and urea, a critical step for the urea cycle. Defects in ARG1 are the cause of argininemia, an autosomal recessive disorder characterized by hyperammonemia. There are several isoforms of mammalian arginase. The type I isoform, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Hepatocellular carcinoma usually shows higher protein expression of ARG1 than normal liver cells.
Immunogen
n/a
Other Names
AI type I arginase; arginase 1, liver; arginase I; arginase, liver; arginase-1; liver-type arginase; type I arginase