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Description
ZPK Polyclonal Antibody. ZPK is a member of serine/threonine protein kinase family. This kinase contains a leucine-zipper domain, and is predominately expressed in neuronal cells. The phosphorylation state of this kinase in synaptic terminals was shown to be regulated by membrane depolarization via calcineurin. This kinase forms heterodimers with leucine zipper containing transcription factors, such as cAMP responsive element binding protein (CREB) and MYC, and thus may play a regulatory role in PKA or retinoic acid induced neuronal differentiation.
Immunogen
n/a
Other Names
DLK, MUK, Zpk, MAPK-upstream kinase, dual leucine zipper bearing kinase, leucine-zipper protein kinase, mitogen activated protein kinase kinase kinase 12, mixed lineage kinase, zipper (leucine) protein kinase