bovine, canine, equine, guinea pig, human, mouse, rabbit, rat
Isotype
n/a
Format
purified
Size
100 μl
Concentration
n/a
Applications
Immunohistochemistry: 5 μg/mL, Western Blot: 2.5 μg/mL
Reviews / Ratings
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Description
P2X1 Polyclonal Antibody. The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with relatively high calcium permeability. Binding to ATP mediates synaptic transmission between neurons and from neurons to smooth muscle, being responsible, for example, for sympathetic vasoconstriction in small arteries, arterioles and vas deferens. Mouse studies suggest that this receptor is essential for normal male reproductive function. It is possible that the development of selective antagonists for this receptor may provide an effective non-hormonal male contraceptive pill.
Immunogen
n/a
Other Names
Purinergic receptor P2X, ligand-gated ion channel, 1, P2X1