Immunohistochemistry (Paraffin): 1:50-1:100, Western Blot: 1:1000
Reviews / Ratings
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Description
P2X7 Polyclonal Antibody. P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression.
Immunogen
n/a
Other Names
P2X7, ATP receptor, P2X purinoceptor 7, P2X7 receptor, P2Z receptor, purinergic receptor P2X7 variant A