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Description
FZR1/CDC20C Polyclonal Antibody, Alexa Fluor? 350 Conjugated. ? Target Background: Key regulator of ligase activity of the anaphase promoting complex/cyclosome (APC/C), which confers substrate specificity upon the complex. Associates with the APC/C in late mitosis, in replacement of CDC20, and activates the APC/C during anaphase and telophase. The APC/C remains active in degrading substrates to ensure that positive regulators of the cell cycle do not accumulate prematurely. At the G1/S transition FZR1 is phosphorylated, leading to its dissociation from the APC/C. Following DNA
Immunogen
KLH conjugated synthetic peptide derived from human FZR1/CDC20C. Immunogen Range: 150-200/496
Other Names
FZR; CDH1; FZR2; HCDH; HCDH1; CDC20C; Fizzy-related protein homolog; CDC20-like protein 1; Cdh1/Hct1 homolog; FZR1; FYR; KIAA1242