Immunoprecipitation: 20 μL/1 mg lysate, Western Blot: 1:1,000
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Description
DUSP12 Polyclonal Antibody. Dual specificity phosphatase (DUSP) inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSPs can be divided into six subgroups on the basis of sequence similarity (PRLs, Cdc14 phosphatases, PTENs, myotubularins, MKPs, atypical DUSPs). DUSP inhibitors might be used to manipulate MAPK and cellular responses in both positive and negative ways. The regulated expression and activity of DUSP family members in different cells and tissues controls MAPK intensity and duration to determine the type of physiological response. DUSP12 (YVH1, GKAP) contains the consensus DUSP catalytic domain as well as an extended C-terminal domain of unknown function, thought t
Immunogen
n/a
Other Names
DUSP1, YVH1, YVH1 protein-tyrosine phosphatase ortholog, dual specificity protein phosphatase 12, dual specificity tyrosine phosphatase YVH1, serine/threonine specific protein phosphatase