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Description
DUSP2 Polyclonal Antibody, Alexa Fluor? 488 Conjugated. ? Target Background: DUSP2 is a dual-specific thr/tyr phosphatase that is a physiologically relevant MAP kinase phosphatase. The gene is located on 2q11.2-q11 and contains 4 exons that span approximately 2.3kb. Under specific stress conditions, p53 regulates transcription of PAC1 through a new p53-binding site, and that PAC1 is necessary and sufficient for p53-mediated apoptosis.
Immunogen
KLH conjugated synthetic peptide derived from human DUSP2
Other Names
Dual specicity phosphatase 2; Dual specicity protein phosphatase 2; Dual specicity protein phosphatase PAC 1; DUSP 2; PAC 1; PAC1; Serine/threonine specic protein phosphatase; DUS2_HUMAN.