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| Antigenic Specificity | CAND1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | purified |
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| Size | 100 μl |
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| Concentration | n/a |
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| Applications | Immunocytochemistry: 1-4 μg/mL, Immunofluorescence: 1-4 μg/mL, Western Blot: 1:100 - 1:250 |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CAND1 Polyclonal Antibody. CAND1 enhances transcription from various types of promoters. It is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site. CAND1 disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. |
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| Immunogen | n/a |
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| Other Names | Cullin-associated and neddylation-dissociated 1; DKFZp434M1414; FLJ10114; FLJ10929; FLJ38691; FLJ90441; KIAA0829; TIP120; TIP120A |
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| Gene, Accession # | Entrez: 55832; Uniprot: Q86VP6 |
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| Catalog # | PA5-65972 |
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| Price | |
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| Order / More Info | CAND1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | n/a |
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