Immunohistochemistry (Paraffin): 1:100-1:1000, Western Blot: 1:500-1:3000
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Description
CHMP4C Polyclonal Antibody. CHMP4C belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).
Immunogen
n/a
Other Names
SNF7-3, Shax3, VPS32C, SNF7 homolog associated with Alix 3, Snf7 homologue associated with Alix 3, charged multivesicular body protein 4c, chromatin modifying protein 4C, chromatin-modifying protein 4c, hSnf7-3, hVps32-3, vacuolar protein sorting-associated protein 32-3, vps32-3