Nucleoside Diphosphate Kinase A, aa1-152, Recombinant, Human
Description
Purity ~95% by SDS-PAGE Purified by immunoaffinity chromatography. Non-metastatic cells 1 (NME1), also known as NM23-H1, originally identified as a candidate metastasis suppressor gene. NME1 is expressed in different tumor types where their levels have been alternatively associated with reduced or increased metastatic potential. Reductions in NME1 expression have been significantly associated with aggressive behavior in melanoma, breast, colon, and gastric carcinomas. On the contrary, high levels of NME1 gene expression are noted in the advanced stage of thyroid carcinomas. Recombinant human NME1 , expressed in E. coli and purified by using conventional chromatography techniques. Source: Recombinant human NME1 (aa1-152) expressed in E. coli (NP_000260). AA Sequence: MANCERTFIA IKPDGVQRGL VGEIIKRFEQ KGFRLVGLKF MQASEDLLKE HYVDLKDRPF FAGLVKYMHS GPVVAMVWEG LNVVKTGRVM LGETNPADSK PGTIRGDFCI QVGRNIIHGS DSVESAEKEI GLWFHPEELV DYTSCAQNWI YE Enzyme Activity: Not determined. This product is recomm
Size
100ug
Concentration
n/a
Applications
n/a
Other Names
Nucleoside Diphosphate Kinase A, aa1-152, Recombinant, Human (NME1, NDP kinase A, AWD, GAAD, NB, NBS, NDPK-A, NM23, NM23-H1)